The Science
The Science Behind the Test
The Human Genome Project was completed in 2003 and the scientists behind HomeDNA Skin Care began uncovering the human skin's unique genetic blueprint. Since then, an additional 17 genetic skin markers have been discovered, opening up a new era in personalized skin management.
HomeDNA Healthy Skin is a scientifically-based DNA test that examines 28 genetic markers (SNPs) in 7 categories associated with skin aging. Each category is graded on a proprietary scale.
1. Collagen Quality
Collagen makes up approximately 75% of skin, and youthful skin is in large part because of healthy collagen levels. While collagen production naturally occurs throughout our lives the quality and quantity varies. As such many people can experience different levels of skin aging attributes based on each individual’s level of collagen quality. Some of the signs associated with this category: sagging, scarring, healing issues, hollowing, accelerated aging, and fine lines.
2. Skin Elasticity
When you are younger, your body has the ability to maintain skin flexibility, but after approximately 40 years of age, skin elasticity can decline due to a group of enzymes called MMPs. MMPs can increase structural damage to the skin and create imbalances that can lead to unstable collagen support leading to loss of skin and structure. Some of the signs associated with this category: increased collagen breakdown, sagging, jowls, nasolabial folds, healing issues, and premature wrinkling.
3. Fine Lines & Wrinkles
Fine lines and wrinkles are not only formed from a decline in collagen levels but also from Advanced Glycation End (AGE) products. AGEs have the ability to target and stick to collagen and elastin fibers causing them to become rigid and brittle. This is sometimes described as rusty springs in a mattress. The effects of glycation at a skin’s cellular level may result in wrinkling, stiff or hardened collagen fibers, loss of elasticity, and compromised skin barrier functions.
4. Sun Protection
Your body is equipped with natural responses that help to break down photo products once they have penetrated your skin. A photochemical process helps assist in breaking down UV rays before they can do any major damage. Some of the signs associated with this category: fine lines and wrinkles, crepe-like/thinning skin, sun sensitivity, skin thickening/leathery skin.
5. Pigmentation
Melanin helps protect your skin by absorbing damaging UV rays when you are exposed to the sun. This exposure to sunlight can also cause your skin to produce more melanin in an attempt to protect the skin. As melanin production increases, skin will begin to tan and darken. The cause of most irregular skin pigmentation is by either an over or under production of melanin in the body. Some of the signs associated with this category: freckles, age spots, rough skin, texture, and discoloration.
6. Skin Antioxidants
A big part of premature skin aging is a result of free radical activity within the body. Free radicals are harmful molecules that are produced naturally from environmental exposures. The role of antioxidants is to help break down the damaging effects of free radicals. Antioxidants can also help slow some of the physical signs of aging to help preserve your skin’s natural glow. Some signs associated with this category: dull skin, uneven tone, blemishes, pigmentation, wrinkles, premature skin aging, and skin dehydration.
7. Skin Sensitivity
Skin sensitivities can create unnecessary stress and trauma to the dermis that can lead to tired and aged cells. This type of trauma can lead to even further sensitivity issues. Understanding if sensitivity may be an issue allows you to keep your skin as stress free as possible. Some of the signs associated with this category: skin dehydration, active ingredient sensitivities, fragrance sensitivities, itching and redness, environmental sensitivities, and premature aging.